United States securities and exchange commission logo May 22, 2023 Pierluigi Paracchi Chief Executive Officer Genenta Science S.p.A. Via Olgettina No. 58 20132 Milan, Italy Re: Genenta Science S.p.A. Registration Statement on Form F-3 Filed May 12, 2023 File No. 333-271901 Dear Pierluigi Paracchi: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Cindy Polynice at 202-551-8707 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Per Chilstrom, Esq.